Subject(s)
Humans , Female , Middle Aged , Skin Neoplasms/drug therapy , Adrenal Cortex Hormones/therapeutic use , Lipomatosis/drug therapy , Nevus/drug therapy , Skin Neoplasms/pathology , Biopsy , Administration, Cutaneous , Treatment Outcome , Dermis/pathology , Lipomatosis/pathology , Nevus/pathologyABSTRACT
Presentamos a una mujer de 75 años, con antecedente de psoriasis a grandes placas, de 40 años de evolución. Luego de múltiples tratamientos tópicos y sistémicos que mejoraron su dermatosis, se observaron placas amarillo-anaranjadas infiltradas, de localización paravertebral. El estudio histopatológico informó la presencia de adipocitos maduros en banda en dermis reticular. Se realizó el diagnóstico de metaplasia lipomatosa. En la piel, la metaplasia lipomatosa es sumamente infrecuente. Se postula que la metaplasia puede ocurrir como consecuencia de la inflamación crónica y severa de la piel.
We report the case of a 75 year-old woman who had been suffering from severe large-plaquepsoriasis during forty years. After multiple topical and systemic treatments her psoriasisimproved and yellowish-orange, dorsal, infiltrated plaques were observed.Histology of skin biopsies showed a band of mature adipocytes in the reticular dermis. Thediagnosis of lipomatous metaplasia was considered.Lipomatous metaplasia of the skin is very infrequent. Up to date, we have found only onereport, in which the authors hypothesize that it can occur as a consequence of severe chronic inflammation of the skin.
Subject(s)
Humans , Aged , Female , Metaplasia/etiology , Adipose Tissue/pathology , Inflammation/complications , Lipomatosis/etiology , Lipomatosis/drug therapy , Skin/pathology , Psoriasis/complicationsABSTRACT
Se describe una serie clínico-patológica de tumores cutáneos habitualmente dolorosos y se revisan las características de cada uno de ellos, lipomatosis dolorosa, neurilemoma, neuroma, nevo azul en tetina de goma, sinovialoma, tumor de células granulosas y tumor glómico